GENES INVOLVED IN SCHIZOPHRENIA IDENTIFIED AT UCL, FOR FIRST TIME (THEY SAY)

 

                                                                     

Quote """Landmark research, involving scientists at UCL, has for the first time identified ten genes with extremely rare protein-disrupting mutations, that significantly increase an individual's risk of developing schizophrenia."""

                                            UCL RESEARCH

                                        2022 Article in Nature

Quote """The findings are the combined work of hundreds of researchers across 45 countries, who analysed DNA from 76,755 people with schizophrenia and 243,649 without it to better understand the genes and biological processes underpinning the condition.  

While previous research has shown associations between schizophrenia and many DNA regions, this is the first to pin-point specific genes""".

NOTE THAT THIS IS A NON-RANDOM SAMPLE. THEREFORE LARGE SAMPLE 

SIZES DO NOT FACILITATE ACCURATE DEDUCTIVE STATISTICAL INFERENCES. 

       HOWEVER,  IF SIMILAR, SUBJECTIVE,CONCLUSIONS WERE REPLICATED 

ACROSS MOST OF THE 45 COUNTRIES THEN THAT WOULD GIVE SOME CREDIBILITY 

TO THE ASSOCIATIONS STATED, 

         POSSIBLE CONFOUNDING VARIABLES SHOULD 

ALSO BE CONSIDERED e.g WERE THE CONTROL GROUP CHOSEN IN 

SOME WAY  THAT MADE THEM LESS LIKELY TO POSSESS THESE 10 GENES?

THE RESEARCH REPORTED CONCERNING BIPOLAR DISORDER SEEMS TO BE OPEN TO QUESTION OWING TO LACK OF VALID DEFINITION FOR THIS SO-CALLED DISORDER, AND LACK OF PREVIOUS BIOLOGICAL BASIS